Assay Detail
Functional
CHEMBL3267777
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Antimicrobial activity against Escherichia coli ATCC 29425 after 3 hrs by microbroth dilution method
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multitarget drug discovery for tuberculosis and other infectious diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.73 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3261883 | — | — | 1 | 5.17 |
| CHEMBL561057 | SQ109 | 2.0 | 1 | 5.07 |
| CHEMBL3261880 | — | — | 1 | 5.07 |
| CHEMBL3261881 | — | — | 1 | 4.89 |
| CHEMBL3261890 | — | — | 1 | 4.44 |
| CHEMBL3261889 | — | — | 1 | 4.34 |
| CHEMBL3261884 | — | — | 1 | 4.12 |
| CHEMBL3261882 | — | — | 1 | - |
| CHEMBL3261885 | — | — | 1 | - |
| CHEMBL3261886 | — | — | 1 | - |
| CHEMBL3261887 | — | — | 1 | - |
| CHEMBL3261888 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3261883 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL561057 | SQ109 | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL3261880 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL3261881 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL3261890 | — | IC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL3261889 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL3261884 | — | IC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL3261882 | — | IC50 | = | 1000000.0 | nM | - |
| CHEMBL3261885 | — | IC50 | = | 1000000.0 | nM | - |
| CHEMBL3261886 | — | IC50 | = | 1000000.0 | nM | - |
| CHEMBL3261887 | — | IC50 | = | 498000.0 | nM | - |
| CHEMBL3261888 | — | IC50 | = | 220000.0 | nM | - |