Assay Detail
Binding
CHEMBL3296599
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human SERT expressed in African green monkey COS7 cells after 2 hrs by scintillation counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent serotonin transporter (CHEMBL228) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Novel and high affinity fluorescent ligands for the serotonin transporter based on (s)-citalopram.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.59 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1508 | ESCITALOPRAM | 4.0 | 1 | 8.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1508 | ESCITALOPRAM | Kd | = | 2.6 | nM | 8.59 |