Assay Detail
ADMET
CHEMBL3296728
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Inhibition of CYP2D6 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.65 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3289811 | — | — | 1 | 4.90 |
| CHEMBL3289803 | — | — | 1 | 4.58 |
| CHEMBL3289806 | — | — | 1 | 4.55 |
| CHEMBL3289813 | — | — | 1 | 4.55 |
| CHEMBL3289805 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3289811 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL3289803 | — | IC50 | = | 26300.0 | nM | 4.58 |
| CHEMBL3289806 | — | IC50 | = | 27900.0 | nM | 4.55 |
| CHEMBL3289813 | — | IC50 | = | 28300.0 | nM | 4.55 |
| CHEMBL3289805 | — | IC50 | > | 30000.0 | nM | - |