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Assay Detail

CHEMBL3300340

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 7 days by serial dilution method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mycobacterium tuberculosis
Confidence 1 — Organism
Curated By Autocuration

Target

Mycobacterium tuberculosis (CHEMBL360)
Type ORGANISM
Organism Mycobacterium tuberculosis

Publication

Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla.
Dasyam N, Munkacsi AB, Fadzilah NH, Senanayake DS, O'Toole RF, Keyzers RA.
J Nat Prod (2014) 77 : 1519 -1523
PubMed 24856903 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.81 4.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL372795 STREPTOMYCIN 4.0 1 4.90
CHEMBL3298696 1 4.71
CHEMBL3298697 1 -
CHEMBL3298698 1 -
CHEMBL3298699 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL372795 STREPTOMYCIN IC50 = 12500.0 nM 4.90
CHEMBL3298696 IC50 = 19400.0 nM 4.71
CHEMBL3298697 IC50 = 114000.0 nM -
CHEMBL3298698 IC50 - -
CHEMBL3298699 IC50 - -