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Assay Detail

CHEMBL3364730

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Immunosuppressive activity in C57Bl/6 mouse lymphocytes assessed as inhibition of cell proliferation co-incubated with BALB/c mouse stimulator lymphocytes after 72 hrs by [3H]-thymidine incorporation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Lymphocyte
Confidence 1 — Organism
Curated By Autocuration

Publication

Biological evaluation of subglutinol a as a novel immunosuppressive agent for inflammation intervention.
Lin R, Kim H, Hong J, Li QJ.
ACS Med Chem Lett (2014) 5 : 485 -490
PubMed 24900866 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL480487 SUBGLUTINOL A 1 7.00
CHEMBL480488 SUBGLUTINOL B 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL480487 SUBGLUTINOL A IC50 = 100.0 nM 7.00
CHEMBL480488 SUBGLUTINOL B IC50 = 100.0 nM 7.00