Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL480488

SUBGLUTINOL B
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C=C1CC[C@H]2[C@]3(C)C[C@H](C=C(C)C)O[C@H]3CC[C@]2(C)[C@@H]1Cc1c(O)c(C)c(C)oc1=O

Basic Information

ChEMBL ID CHEMBL480488
Name SUBGLUTINOL B
Phase Preclinical
Structure Type MOL
InChI Key SXNPXUJAUIINIU-ZZJUZBICSA-N
3
Targets
4
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

426.6
MW (Da)
6.02
ALogP
4
HBA
1
HBD
59.7
PSA (Ų)
0.60
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C27H38O4
MW 426.60
Aromatic Rings 1
Heavy Atoms 31
NP-Likeness 2.61

Activity Summary

IC50 4 meas. best 7.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
NON-PROTEIN TARGET
CHEMBL3879801
IC50 7.0 7.0 100.0 1
Lymphocyte
CHEMBL612599
IC50 7.0 7.0 100.0 1
Thymocyte
CHEMBL613302
IC50 7.0 7.0 100.0 2

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
14987067 10.1021/np030397v Lymphocyte 1
14987067 10.1021/np030397v Thymocyte 1
24900866 10.1021/ml4004809 NON-PROTEIN TARGET 1
24900866 10.1021/ml4004809 Thymocyte 1

Data from ChEMBL 36 via Core Engine