Assay Detail
Binding
CHEMBL3367185
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Inhibition of AP-1 (unknown origin) by FRET assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small molecule inhibitors targeting activator protein 1 (AP-1).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.36 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1807644 | NOTHOSPONDIN | — | 1 | 6.89 |
| CHEMBL458347 | GLAUCARUBINONE | — | 1 | 5.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1807644 | NOTHOSPONDIN | EC50 | = | 130.0 | nM | 6.89 |
| CHEMBL458347 | GLAUCARUBINONE | EC50 | = | 1490.0 | nM | 5.83 |