Assay Detail
Functional
CHEMBL3369161
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vivo induction of GK translocation from nucleus to cytoplasm in po dosed insulin-resistant db/db mouse liver measured at 6 hrs by immunohistochemistry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 4. Exploration of a novel binding pocket.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.69 | 6.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3319549 | — | — | 1 | 6.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3319549 | — | EC50 | = | 205.0 | nM | 6.69 |