Assay Detail
Binding
CHEMBL3370551
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to rat CGRP receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Calcitonin gene-related peptide type 1 receptor (CHEMBL4755) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Calcitonin gene-related peptide receptor antagonists: new therapeutic agents for migraine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.24 | 8.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207197 | OLCEGEPANT | 2.0 | 1 | 8.47 |
| CHEMBL1910936 | MK3207 | 2.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207197 | OLCEGEPANT | Ki | = | 3.4 | nM | 8.47 |
| CHEMBL1910936 | MK3207 | Ki | = | 10.0 | nM | 8.00 |