Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3374066

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against mouse B16F10 cells after 48 to 72 hrs by MTT assay
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type B16-F10
Confidence 1 — Organism
Curated By Autocuration

Publication

C-glycoside mimetics inhibit glioma stem cell proliferation, migration, and invasion.
Clarion L, Jacquard C, Sainte-Catherine O, Decoux M, Loiseau S, Rolland M, Lecouvey M, Hugnot JP, Volle JN, Virieux D, Pirat JL, Bakalara N.
J Med Chem (2014) 57 : 8293 -8306
PubMed 25211466 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 18 5.40 5.99

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3343646 1 5.99
CHEMBL3343415 1 5.79
CHEMBL3343643 1 5.71
CHEMBL3343644 1 5.70
CHEMBL3343645 1 5.69
CHEMBL3343414 1 5.68
CHEMBL3343641 1 5.59
CHEMBL3343642 1 5.33
CHEMBL3343407 1 5.00
CHEMBL3343408 1 4.99
CHEMBL3343409 1 4.98
CHEMBL3343413 1 4.87
CHEMBL3343647 1 4.83
CHEMBL3343416 1 -
CHEMBL3341777 1 -
CHEMBL3343412 1 -
CHEMBL3343411 1 -
CHEMBL3343410 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3343646 IC50 = 1020.0 nM 5.99
CHEMBL3343415 IC50 = 1640.0 nM 5.79
CHEMBL3343643 IC50 = 1960.0 nM 5.71
CHEMBL3343644 IC50 = 2020.0 nM 5.70
CHEMBL3343645 IC50 = 2050.0 nM 5.69
CHEMBL3343414 IC50 = 2080.0 nM 5.68
CHEMBL3343641 IC50 = 2590.0 nM 5.59
CHEMBL3343642 IC50 = 4690.0 nM 5.33
CHEMBL3343407 IC50 = 9950.0 nM 5.00
CHEMBL3343408 IC50 = 10180.0 nM 4.99
CHEMBL3343409 IC50 = 10380.0 nM 4.98
CHEMBL3343413 IC50 = 13480.0 nM 4.87
CHEMBL3343647 IC50 = 14870.0 nM 4.83
CHEMBL3343416 IC50 > 100000.0 nM -
CHEMBL3341777 IC50 > 100000.0 nM -
CHEMBL3343412 IC50 > 100000.0 nM -
CHEMBL3343411 IC50 > 100000.0 nM -
CHEMBL3343410 IC50 > 100000.0 nM -