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Assay Detail

CHEMBL3382028

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Bel7402 cells by MTT assay
23
Total Activities
23
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Bel-7402
Confidence 1 — Organism
Curated By Autocuration

Publication

Bioactive spirobisnaphthalenes from the endophytic fungus Berkleasmium sp.
Shan T, Tian J, Wang X, Mou Y, Mao Z, Lai D, Dai J, Peng Y, Zhou L, Wang M.
J Nat Prod (2014) 77 : 2151 -2160
PubMed 25237727 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 23 5.35 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3342632 1 5.60
CHEMBL3342627 1 5.48
CHEMBL89475 1 5.29
CHEMBL65 CAMPTOTHECIN -1.0 1 5.20
CHEMBL3342628 1 5.19
CHEMBL3342626 1 -
CHEMBL153990 1 -
CHEMBL3342629 1 -
CHEMBL3342630 1 -
CHEMBL3342631 1 -
CHEMBL3342633 1 -
CHEMBL3342634 1 -
CHEMBL3342635 1 -
CHEMBL3342636 1 -
CHEMBL3342637 1 -
CHEMBL3342638 1 -
CHEMBL3342639 1 -
CHEMBL3342640 1 -
CHEMBL3342641 1 -
CHEMBL3342642 1 -
CHEMBL3342643 1 -
CHEMBL457641 PALMARUMYCIN CP17 1 -
CHEMBL3342644 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3342632 IC50 = 2500.0 nM 5.60
CHEMBL3342627 IC50 = 3300.0 nM 5.48
CHEMBL89475 IC50 = 5100.0 nM 5.29
CHEMBL65 CAMPTOTHECIN IC50 = 6300.0 nM 5.20
CHEMBL3342628 IC50 = 6400.0 nM 5.19
CHEMBL3342626 IC50 > 10000.0 nM -
CHEMBL153990 IC50 > 10000.0 nM -
CHEMBL3342629 IC50 > 10000.0 nM -
CHEMBL3342630 IC50 > 10000.0 nM -
CHEMBL3342631 IC50 > 10000.0 nM -
CHEMBL3342633 IC50 > 10000.0 nM -
CHEMBL3342634 IC50 > 10000.0 nM -
CHEMBL3342635 IC50 > 10000.0 nM -
CHEMBL3342636 IC50 > 10000.0 nM -
CHEMBL3342637 IC50 > 10000.0 nM -
CHEMBL3342638 IC50 > 10000.0 nM -
CHEMBL3342639 IC50 > 10000.0 nM -
CHEMBL3342640 IC50 > 10000.0 nM -
CHEMBL3342641 IC50 > 10000.0 nM -
CHEMBL3342642 IC50 > 10000.0 nM -
CHEMBL3342643 IC50 > 10000.0 nM -
CHEMBL457641 PALMARUMYCIN CP17 IC50 > 10000.0 nM -
CHEMBL3342644 IC50 > 10000.0 nM -