Assay Detail
Functional
CHEMBL3383450
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Cytotoxicity against BL2 cells (unknown origin) assessed as cell killing after 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Not specified |
| Cell Type | BL2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.07 | 5.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3339156 | — | — | 1 | 5.07 |
| CHEMBL3339152 | — | — | 1 | - |
| CHEMBL3339153 | — | — | 1 | - |
| CHEMBL3339154 | — | — | 1 | - |
| CHEMBL3339155 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3339156 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL3339152 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL3339153 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL3339154 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL3339155 | — | IC50 | > | 20000.0 | nM | - |