Assay Detail
Functional
CHEMBL3384510
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Cytotoxicity against human PC3 cells after 72 hrs by WST-1 assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tailor-made fluorescent trilobolide to study its biological relevance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.57 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3343188 | — | — | 1 | 6.30 |
| CHEMBL3343190 | — | — | 1 | 5.50 |
| CHEMBL3343189 | — | — | 1 | 5.42 |
| CHEMBL3343191 | — | — | 1 | 5.39 |
| CHEMBL3343406 | — | — | 1 | 5.25 |
| CHEMBL3343192 | — | — | 1 | - |
| CHEMBL3343405 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3343188 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3343190 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL3343189 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL3343191 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL3343406 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL3343192 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3343405 | — | IC50 | > | 50000.0 | nM | - |