Compound Detail
CHEMBL3343406
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Basic Information
| ChEMBL ID | CHEMBL3343406 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GUHHEAYOTAJBPT-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
192.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | IC50 | 5.82 | 5.5267 | 1500.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | IC50 | = | 1500.0 | nM | 5.82 | Cytotoxicity against human PC3 cells after 24 hrs by WST-1 assay | 25197766 |
| NON-PROTEIN TARGET | IC50 | = | 3100.0 | nM | 5.51 | Cytotoxicity against human PC3 cells after 48 hrs by WST-1 assay | 25197766 |
| NON-PROTEIN TARGET | IC50 | = | 5600.0 | nM | 5.25 | Cytotoxicity against human PC3 cells after 72 hrs by WST-1 assay | 25197766 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25197766 | 10.1021/jm500690j | NON-PROTEIN TARGET | 6 |
| 25197766 | 10.1021/jm500690j | LNCaP | 3 |
| 25197766 | 10.1021/jm500690j | C2C12 | 3 |
| 25197766 | 10.1021/jm500690j | U2OS | 3 |
| 25197766 | 10.1021/jm500690j | MCF7 | 3 |
| 25197766 | 10.1021/jm500690j | HT-29 | 3 |
| 25197766 | 10.1021/jm500690j | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine