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Assay Detail

CHEMBL3384520

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MIAPaCa2 cells after 24 hrs by WST-1 assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MIA PaCa-2
Confidence 1 — Organism
Curated By Autocuration

Publication

Tailor-made fluorescent trilobolide to study its biological relevance.
Jurášek M, Rimpelová S, Kmoníčková E, Drašar P, Ruml T.
J Med Chem (2014) 57 : 7947 -7954
PubMed 25197766 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.76 4.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3343188 1 4.76
CHEMBL3343189 1 -
CHEMBL3343190 1 -
CHEMBL3343191 1 -
CHEMBL3343192 1 -
CHEMBL3343405 1 -
CHEMBL3343406 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3343188 IC50 = 17400.0 nM 4.76
CHEMBL3343189 IC50 > 50000.0 nM -
CHEMBL3343190 IC50 > 50000.0 nM -
CHEMBL3343191 IC50 > 50000.0 nM -
CHEMBL3343192 IC50 > 50000.0 nM -
CHEMBL3343405 IC50 > 50000.0 nM -
CHEMBL3343406 IC50 > 50000.0 nM -