Assay Detail
ADMET
CHEMBL3390676
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2D6 (unknown origin) using bufuralol substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.58 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3325526 | — | — | 1 | 6.58 |
| CHEMBL3325537 | — | — | 1 | 6.57 |
| CHEMBL3325551 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3325526 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL3325537 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL3325551 | — | IC50 | > | 10000.0 | nM | - |