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Assay Detail

CHEMBL3391007

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MDM2 (unknown origin) by surface plasmon resonance analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

E3 ubiquitin-protein ligase Mdm2 (CHEMBL5023)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4)
Macchiarulo A, Giacche N, Carotti A, Moretti F, Pellicciari R
Medchemcomm (2011) 2 : 455 -465
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.31 9.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3347580 1 9.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3347580 Kd = 0.49 nM 9.31