Assay Detail
Binding
CHEMBL3391360
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Agonist activity at human mGluR2 receptor expressed in HEK cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A highly selective agonist for the metabotropic glutamate receptor mGluR2
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.84 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | 5.75 |
| CHEMBL3347671 | — | — | 1 | 5.00 |
| CHEMBL3347670 | — | — | 1 | 4.64 |
| CHEMBL334842 | — | — | 1 | 4.43 |
| CHEMBL131922 | — | — | 1 | 4.40 |
| CHEMBL3347672 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL575060 | GLUTAMIC ACID | EC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL3347671 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL3347670 | — | EC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL334842 | — | EC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL131922 | — | EC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL3347672 | — | EC50 | = | 251000.0 | nM | - |