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Assay Detail

CHEMBL3532882

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of glycogen phosphorylase in ob/ob mouse
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Autocuration

Target

Mus musculus (CHEMBL375)
Type ORGANISM
Organism Mus musculus

Publication

Absorption, elimination, and metabolism of CS-1036, a novel α-amylase inhibitor in rats and monkeys, and the relationship between gastrointestinal distribution and suppression of glucose absorption.
Honda T, Kaneno-Urasaki Y, Murai T, Kakuta M, Nasu H, Namba E, Koga T, Okuno A, Izumi T.
Drug Metab Dispos (2013) 41 : 878 -887
PubMed 23378626 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.41 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL80254 1 6.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL80254 Ki = 392.0 nM 6.41