Assay Detail
ADMET
CHEMBL3583779
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Cytotoxicity against human DU145 cells after 48 hrs by sulforhodamine B assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Selective Inhibition of Bacterial Topoisomerase I by alkynyl-bisbenzimidazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.52 | 5.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3581010 | — | — | 1 | 5.67 |
| CHEMBL343002 | — | — | 1 | 5.37 |
| CHEMBL3581011 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3581010 | — | IC50 | = | 2120.0 | nM | 5.67 |
| CHEMBL343002 | — | IC50 | = | 4250.0 | nM | 5.37 |
| CHEMBL3581011 | — | IC50 | > | 10000.0 | nM | - |