Assay Detail
Functional
CHEMBL3584571
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Cytotoxicity against human HL60 cells incubated for 48 hrs by MTT assay
23
Total Activities
23
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive Limonoid Constituents of Munronia henryi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 23 | 5.84 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2269413 | MUNRONIN A | — | 1 | 6.36 |
| CHEMBL3085392 | PRIEURIANIN | — | 1 | 5.32 |
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | - |
| CHEMBL2269412 | MUNRONIN B | — | 1 | - |
| CHEMBL2269411 | MUNRONIN C | — | 1 | - |
| CHEMBL2269410 | MUNRONIN D | — | 1 | - |
| CHEMBL2269409 | MUNRONIN E | — | 1 | - |
| CHEMBL2269408 | MUNRONIN F | — | 1 | - |
| CHEMBL3581410 | — | — | 1 | - |
| CHEMBL3581411 | — | — | 1 | - |
| CHEMBL3581412 | — | — | 1 | - |
| CHEMBL3581413 | — | — | 1 | - |
| CHEMBL3581414 | — | — | 1 | - |
| CHEMBL3581415 | — | — | 1 | - |
| CHEMBL3581416 | — | — | 1 | - |
| CHEMBL3581417 | — | — | 1 | - |
| CHEMBL1077058 | CHISONIMBOLININ F | — | 1 | - |
| CHEMBL3581418 | — | — | 1 | - |
| CHEMBL3581419 | — | — | 1 | - |
| CHEMBL2229170 | MOMBASOL | — | 1 | - |
| CHEMBL2229166 | MUNRONOID L | — | 1 | - |
| CHEMBL3581420 | — | — | 1 | - |
| CHEMBL3581421 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2269413 | MUNRONIN A | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL3085392 | PRIEURIANIN | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL428647 | PACLITAXEL | IC50 | < | 8.0 | nM | - |
| CHEMBL2269412 | MUNRONIN B | IC50 | > | 10000.0 | nM | - |
| CHEMBL2269411 | MUNRONIN C | IC50 | > | 10000.0 | nM | - |
| CHEMBL2269410 | MUNRONIN D | IC50 | > | 10000.0 | nM | - |
| CHEMBL2269409 | MUNRONIN E | IC50 | > | 10000.0 | nM | - |
| CHEMBL2269408 | MUNRONIN F | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581410 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581411 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581412 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581413 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581414 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581415 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581416 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581417 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1077058 | CHISONIMBOLININ F | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581418 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581419 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2229170 | MOMBASOL | IC50 | > | 10000.0 | nM | - |
| CHEMBL2229166 | MUNRONOID L | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581420 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3581421 | — | IC50 | > | 10000.0 | nM | - |