Assay Detail
Functional
CHEMBL3598651
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Antiproliferative activity against human MOLT3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phospholipid derivatives of cladribine and fludarabine: synthesis and biological properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.59 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096882 | FLUDARABINE PHOSPHATE | 4.0 | 1 | 6.02 |
| CHEMBL1619 | CLADRIBINE | 4.0 | 1 | 5.64 |
| CHEMBL3597147 | — | — | 1 | 5.10 |
| CHEMBL3597148 | — | — | 1 | - |
| CHEMBL3597149 | — | — | 1 | - |
| CHEMBL3596207 | — | — | 1 | - |
| CHEMBL3597225 | — | — | 1 | - |
| CHEMBL3597226 | — | — | 1 | - |
| CHEMBL3597227 | — | — | 1 | - |
| CHEMBL3597228 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096882 | FLUDARABINE PHOSPHATE | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL1619 | CLADRIBINE | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3597147 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3597148 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597149 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3596207 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597225 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597226 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597227 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3597228 | — | IC50 | > | 100000.0 | nM | - |