Assay Detail
Functional
CHEMBL3606612
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Cytotoxicity against human DU145 cells after 24 hrs by FMCA
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hedgehog inhibitors from Withania somnifera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.25 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2047410 | — | — | 1 | 5.75 |
| CHEMBL517080 | WITHAFERIN A | 1.0 | 1 | 5.60 |
| CHEMBL3234469 | — | — | 1 | 4.97 |
| CHEMBL469945 | — | — | 1 | 4.66 |
| CHEMBL1934583 | — | — | 1 | - |
| CHEMBL1934585 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2047410 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL517080 | WITHAFERIN A | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL3234469 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL469945 | — | IC50 | = | 21700.0 | nM | 4.66 |
| CHEMBL1934583 | — | IC50 | > | 25000.0 | nM | - |
| CHEMBL1934585 | — | IC50 | > | 25000.0 | nM | - |