Assay Detail
Functional
CHEMBL3611249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV by syncytial plaque assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus (CHEMBL613758) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus |
Publication
Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.85 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | 2.0 | 1 | 8.00 |
| CHEMBL331237 | TRICIRIBINE | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL331237 | TRICIRIBINE | IC50 | = | 20.0 | nM | 7.70 |