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Assay Detail

CHEMBL3630588

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at muscarinic M5 receptor (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Muscarinic acetylcholine receptor M5 (CHEMBL2035)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular hybridization yields triazole bronchodilators for the treatment of COPD.
Jones LH, Burrows J, Feeder N, Glossop P, James K, Jones RM, Kenyon AS, Patel S, Roberts DF, Selby MD, Strang RS, Stuart EF, Trevethick MA, Watson J, Wright KN, Clarke N.
Bioorg Med Chem Lett (2015) 25 : 5121 -5126
PubMed 26471092 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.96 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3629360 1 8.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3629360 Ki = 1.1 nM 8.96