Assay Detail
Binding
CHEMBL3630593
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at beta2 adrenoceptor in guinea pig trachea assessed as inhibition of histamine-induced contraction
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular hybridization yields triazole bronchodilators for the treatment of COPD.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.23 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1263 | SALMETEROL | 4.0 | 1 | 8.57 |
| CHEMBL3629360 | — | — | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1263 | SALMETEROL | EC50 | = | 2.7 | nM | 8.57 |
| CHEMBL3629360 | — | EC50 | = | 12.9 | nM | 7.89 |