Assay Detail
Binding
CHEMBL3635484
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human CETP in buffer assessed as transfer of [3H]-cholesteryl ester from HDL donor particles to LDL acceptor particles
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Applications of Fluorine in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.27 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL297971 | — | — | 1 | 6.70 |
| CHEMBL288060 | — | — | 1 | 6.32 |
| CHEMBL416623 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL297971 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL288060 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL416623 | — | IC50 | = | 1600.0 | nM | 5.80 |