Assay Detail
Functional
CHEMBL3635486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 infected in human PBM cells assessed as inhibition of viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | PBM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Applications of Fluorine in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.75 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3632868 | — | — | 1 | 6.14 |
| CHEMBL501916 | LODENOSINE | 2.0 | 1 | 5.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3632868 | — | EC50 | = | 720.0 | nM | 6.14 |
| CHEMBL501916 | LODENOSINE | EC50 | = | 4400.0 | nM | 5.36 |