Compound Detail
CHEMBL3632868
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Basic Information
| ChEMBL ID | CHEMBL3632868 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MUERFVHFNIYBRA-XTWHOAMZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
271.2
MW (Da)
-0.03
ALogP
7
HBA
2
HBD
99.1
PSA (Ų)
0.80
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.14
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 6.14 | 6.14 | 720.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 720.0 | nM | 6.14 | Antiviral activity against HIV1 infected in human PBM cells assessed as inhibiti... | 26200936 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26200936 | 10.1021/acs.jmedchem.5b00258 | Human immunodeficiency virus 1 | 1 |
Data from ChEMBL 36 via Core Engine