Assay Detail
Functional
CHEMBL3637084
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.88 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633921 | — | — | 1 | 7.06 |
| CHEMBL3633920 | — | — | 1 | 6.99 |
| CHEMBL3633919 | — | — | 1 | 6.98 |
| CHEMBL3633923 | — | — | 1 | 6.94 |
| CHEMBL3633918 | — | — | 1 | 6.67 |
| CHEMBL3633922 | — | — | 1 | 6.65 |
| CHEMBL3633924 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633921 | — | IC50 | = | 86.5 | nM | 7.06 |
| CHEMBL3633920 | — | IC50 | = | 102.0 | nM | 6.99 |
| CHEMBL3633919 | — | IC50 | = | 104.0 | nM | 6.98 |
| CHEMBL3633923 | — | IC50 | = | 116.0 | nM | 6.94 |
| CHEMBL3633918 | — | IC50 | = | 215.0 | nM | 6.67 |
| CHEMBL3633922 | — | IC50 | = | 226.0 | nM | 6.65 |
| CHEMBL3633924 | — | IC50 | - | — | - |