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Assay Detail

CHEMBL3705634

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Radioligand Binding Assay: Radioligand binding assay using TAAR1.
ChEMBL ↗
208
Total Activities
208
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Trace amine-associated receptor 1 (CHEMBL4908) ↗
Type SINGLE PROTEIN
Organism Mus musculus

Publication

2-aminooxazolines as TAAR1 ligands
(2013)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 208 8.63 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3680165 — — 1 10.00
CHEMBL3684812 — — 1 9.70
CHEMBL3680140 — — 1 9.70
CHEMBL3684760 — — 1 9.52
CHEMBL3684906 — — 1 9.52
CHEMBL3680156 — — 1 9.40
CHEMBL3684796 — — 1 9.40
CHEMBL3684873 — — 1 9.40
CHEMBL3684922 — — 1 9.40
CHEMBL3680124 — — 1 9.30
CHEMBL3684918 — — 1 9.22
CHEMBL3680154 — — 1 9.22
CHEMBL3684850 — — 1 9.22
CHEMBL3684834 — — 1 9.22
CHEMBL3684791 — — 1 9.22
CHEMBL3680157 — — 1 9.15
CHEMBL3680134 — — 1 9.15
CHEMBL3684772 — — 1 9.15
CHEMBL3684763 — — 1 9.15
CHEMBL3680146 — — 1 9.10
CHEMBL3680129 — — 1 9.10
CHEMBL3684868 — — 1 9.10
CHEMBL3684803 — — 1 9.10
CHEMBL3684804 — — 1 9.10
CHEMBL3680151 — — 1 9.10
CHEMBL3684891 — — 1 9.10
CHEMBL3684822 — — 1 9.05
CHEMBL3684880 — — 1 9.05
CHEMBL3680128 — — 1 9.05
CHEMBL3684765 — — 1 9.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3680165 — Ki = 0.1 nM 10.00
CHEMBL3680140 — Ki = 0.2 nM 9.70
CHEMBL3684812 — Ki = 0.2 nM 9.70
CHEMBL3684760 — Ki = 0.3 nM 9.52
CHEMBL3684906 — Ki = 0.3 nM 9.52
CHEMBL3684922 — Ki = 0.4 nM 9.40
CHEMBL3680156 — Ki = 0.4 nM 9.40
CHEMBL3684796 — Ki = 0.4 nM 9.40
CHEMBL3684873 — Ki = 0.4 nM 9.40
CHEMBL3680124 — Ki = 0.5 nM 9.30
CHEMBL3684834 — Ki = 0.6 nM 9.22
CHEMBL3684850 — Ki = 0.6 nM 9.22
CHEMBL3680154 — Ki = 0.6 nM 9.22
CHEMBL3684918 — Ki = 0.6 nM 9.22
CHEMBL3684791 — Ki = 0.6 nM 9.22
CHEMBL3680134 — Ki = 0.7 nM 9.15
CHEMBL3680157 — Ki = 0.7 nM 9.15
CHEMBL3684772 — Ki = 0.7 nM 9.15
CHEMBL3684763 — Ki = 0.7 nM 9.15
CHEMBL3680129 — Ki = 0.8 nM 9.10
CHEMBL3684891 — Ki = 0.8 nM 9.10
CHEMBL3680151 — Ki = 0.8 nM 9.10
CHEMBL3684804 — Ki = 0.8 nM 9.10
CHEMBL3684803 — Ki = 0.8 nM 9.10
CHEMBL3680146 — Ki = 0.8 nM 9.10
CHEMBL3684868 — Ki = 0.8 nM 9.10
CHEMBL3680128 — Ki = 0.9 nM 9.05
CHEMBL3684880 — Ki = 0.9 nM 9.05
CHEMBL3684765 — Ki = 0.9 nM 9.05
CHEMBL3684822 — Ki = 0.9 nM 9.05
CHEMBL3684915 — Ki = 0.9 nM 9.05
CHEMBL3684778 — Ki = 0.9 nM 9.05
CHEMBL3684854 — Ki = 0.9 nM 9.05
CHEMBL3680152 — Ki = 1.0 nM 9.00
CHEMBL3684769 — Ki = 1.0 nM 9.00
CHEMBL3684836 — Ki = 1.0 nM 9.00
CHEMBL3684889 — Ki = 1.0 nM 9.00
CHEMBL3684914 — Ki = 1.0 nM 9.00
CHEMBL3684779 — Ki = 1.0 nM 9.00
CHEMBL3684784 — Ki = 1.0 nM 9.00
CHEMBL3680161 — Ki = 1.1 nM 8.96
CHEMBL3684856 — Ki = 1.1 nM 8.96
CHEMBL3680150 — Ki = 1.1 nM 8.96
CHEMBL3684861 — Ki = 1.1 nM 8.96
CHEMBL3680130 — Ki = 1.1 nM 8.96
CHEMBL3680135 — Ki = 1.1 nM 8.96
CHEMBL3684877 — Ki = 1.1 nM 8.96
CHEMBL3684793 — Ki = 1.1 nM 8.96
CHEMBL3684773 — Ki = 1.2 nM 8.92
CHEMBL3684789 — Ki = 1.2 nM 8.92