Assay Detail
Binding
CHEMBL3707983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition Assay: Inhibition assay using P450 CYP enzymes.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
17Beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of hormone-related diseases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.49 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3645217 | — | — | 1 | 4.64 |
| CHEMBL3645215 | — | — | 1 | 4.49 |
| CHEMBL3645225 | — | — | 1 | 4.41 |
| CHEMBL1650658 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3645217 | — | IC50 | = | 22900.0 | nM | 4.64 |
| CHEMBL3645215 | — | IC50 | = | 32560.0 | nM | 4.49 |
| CHEMBL3645225 | — | IC50 | = | 39350.0 | nM | 4.41 |
| CHEMBL1650658 | — | IC50 | = | 40000.0 | nM | 4.40 |