Assay Detail
Functional
CHEMBL3743799
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against O'nyong-nyong virus infected in HEK293T cells assessed as inhibition of infectivity measured at 24 hrs postinfection by FITC/DAPI staining based array scan VTI HCS reader analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Onyong-nyong virus |
| Cell Type | HEK-293T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Trisubstituted Thieno[3,2-b]pyrrole 5-Carboxamides as Potent Inhibitors of Alphaviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.17 | 5.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3741103 | — | — | 1 | 5.59 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3741103 | — | EC50 | = | 2580.0 | nM | 5.59 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 18400.0 | nM | 4.74 |