Assay Detail
Binding
CHEMBL3756317
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to SERT (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent serotonin transporter (CHEMBL228) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.05 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3753894 | — | — | 1 | 7.52 |
| CHEMBL478 | CHLOROPHENYLPIPERAZINE | 2.0 | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3753894 | — | Ki | = | 30.4 | nM | 7.52 |
| CHEMBL478 | CHLOROPHENYLPIPERAZINE | Ki | = | 271.0 | nM | 6.57 |