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Assay Detail

CHEMBL3760689

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Partial agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL233)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Multitarget opioid ligands in pain relief: New players in an old game.
Turnaturi R, Aricò G, Ronsisvalle G, Parenti C, Pasquinucci L.
Eur J Med Chem (2016) 108 : 211 -228
PubMed 26656913 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Emax 1 - -
EC50 1 8.89 8.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL147511 1 8.89
CHEMBL146756 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL147511 EC50 = 1.3 nM 8.89
CHEMBL146756 Emax = 42.0 % -