Assay Detail
Binding
CHEMBL3768265
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant 5-HT5 receptor (unknown origin) after 1.5 hrs by radioligand displacement assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel N-acyl-carbazole derivatives as 5-HT7R antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.93 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3763779 | — | — | 1 | 8.30 |
| CHEMBL3764133 | — | — | 1 | 6.47 |
| CHEMBL3764335 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3763779 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL3764133 | — | Ki | = | 337.0 | nM | 6.47 |
| CHEMBL3764335 | — | Ki | = | 933.0 | nM | 6.03 |