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Assay Detail

CHEMBL3772624

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Functional
Antimetastatic activity against human T47D cells assessed as inhibition of cell migration after 12 hrs by transwell migration assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type T47D
Confidence 1 — Organism
Curated By Autocuration

Target

T47D (CHEMBL614361)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents.
Cui HW, Peng S, Gu XZ, Chen H, He Y, Gao W, Lv F, Wang JH, Wang Y, Xie J, Liu MY, Yi Z, Qiu WW.
Eur J Med Chem (2016) 111 : 126 -137
PubMed 26866967 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.38 6.38
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3769913 2 6.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3769913 IC50 = 420.0 nM 6.38
CHEMBL3769913 Inhibition - % -