Assay Detail
Binding
CHEMBL3772722
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cGMP stimulated human PDE2A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
cGMP-dependent 3',5'-cyclic phosphodiesterase (CHEMBL2652) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Selective inhibitors of phosphodiesterases: therapeutic promise for neurodegenerative disorders
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.22 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL370962 | — | — | 1 | 8.33 |
| CHEMBL296435 | (+)-EHNA | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL370962 | — | IC50 | = | 4.7 | nM | 8.33 |
| CHEMBL296435 | (+)-EHNA | IC50 | = | 800.0 | nM | 6.10 |