Assay Detail

CHEMBL3777304

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity to human mu opioid receptor

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Mu-type opioid receptor (CHEMBL233) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Mu-type opioid receptor (CHEMBL233) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Mu-type opioid receptor

CHEMBL233

Anchored from Assay target.

Protein identity Mu-type opioid receptor

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Mu-type opioid receptor (CHEMBL233) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Tactical Approaches to Interconverting GPCR Agonists and Antagonists.

Dosa PI, Amin EA.
J Med Chem (2016) 59 : 810 -840
PubMed 26390077 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	2	9.36	9.44

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL415284	NALORPHINE	2.0	1	9.44
CHEMBL70	MORPHINE	4.0	1	9.28

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL415284	NALORPHINE	Ki	=	0.36	nM	9.44
CHEMBL70	MORPHINE	Ki	=	0.53	nM	9.28