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Assay Detail

CHEMBL3796433

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ROCK-1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Rho-associated protein kinase 1 (CHEMBL3231)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A review on ROCK-II inhibitors: From molecular modelling to synthesis.
Shah S, Savjani J.
Bioorg Med Chem Lett (2016) 26 : 2383 -2391
PubMed 27080184 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3793353 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3793353 IC50 = 30.0 nM 7.52