Assay Detail
Functional
CHEMBL3807496
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reduction of blood lymphocyte level in BALB/c mouse administered through oral gavage after 24 hrs by hematology analysis
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.18 | 8.25 |
| ED50 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL114606 | — | — | 2 | 8.25 |
| CHEMBL3806205 | — | — | 2 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL114606 | — | EC50 | = | 5.6 | nM | 8.25 |
| CHEMBL3806205 | — | EC50 | = | 7.9 | nM | 8.10 |
| CHEMBL114606 | — | ED50 | = | 0.017 | mg.kg-1 | - |
| CHEMBL3806205 | — | ED50 | = | 0.12 | mg.kg-1 | - |