Assay Detail
Binding
CHEMBL3812012
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]naloxone from human MOR expressed in CHO-K1 cell membranes after 60 mins by microbeta scintillation counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Potent and Selective Agonists of δ Opioid Receptor by Revisiting the "Message-Address" Concept.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.79 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1400 | O-DESMETHYL TRAMADOL | — | 1 | 7.96 |
| CHEMBL1066 | (R,R)-TRAMADOL | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1400 | O-DESMETHYL TRAMADOL | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL1066 | (R,R)-TRAMADOL | Ki | = | 2400.0 | nM | 5.62 |