Assay Detail
Functional
CHEMBL3872005
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Hep 3B2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.93 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3926548 | — | — | 1 | 5.09 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.03 |
| CHEMBL3953142 | — | — | 1 | 4.92 |
| CHEMBL3928791 | — | — | 1 | 4.90 |
| CHEMBL453802 | LUPENYL ACETATE | — | 1 | 4.73 |
| CHEMBL3973883 | — | — | 1 | - |
| CHEMBL3926810 | — | — | 1 | - |
| CHEMBL3962920 | — | — | 1 | - |
| CHEMBL404387 | JOLKINOLIDE B | — | 1 | - |
| CHEMBL3954187 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3926548 | — | IC50 | = | 8146.0 | nM | 5.09 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 9360.0 | nM | 5.03 |
| CHEMBL3953142 | — | IC50 | = | 12012.0 | nM | 4.92 |
| CHEMBL3928791 | — | IC50 | = | 12522.0 | nM | 4.90 |
| CHEMBL453802 | LUPENYL ACETATE | IC50 | = | 18692.0 | nM | 4.73 |
| CHEMBL3973883 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3926810 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3962920 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL404387 | JOLKINOLIDE B | IC50 | > | 100000.0 | nM | - |
| CHEMBL3954187 | — | IC50 | > | 100000.0 | nM | - |