Assay Detail
Functional
CHEMBL3872006
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Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.76 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3953142 | — | — | 1 | 5.03 |
| CHEMBL3928791 | — | — | 1 | 4.92 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.78 |
| CHEMBL404387 | JOLKINOLIDE B | — | 1 | 4.55 |
| CHEMBL453802 | LUPENYL ACETATE | — | 1 | 4.53 |
| CHEMBL3926548 | — | — | 1 | - |
| CHEMBL3954187 | — | — | 1 | - |
| CHEMBL3962920 | — | — | 1 | - |
| CHEMBL3926810 | — | — | 1 | - |
| CHEMBL3973883 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3953142 | — | IC50 | = | 9379.6 | nM | 5.03 |
| CHEMBL3928791 | — | IC50 | = | 11907.0 | nM | 4.92 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 16630.0 | nM | 4.78 |
| CHEMBL404387 | JOLKINOLIDE B | IC50 | = | 28238.0 | nM | 4.55 |
| CHEMBL453802 | LUPENYL ACETATE | IC50 | = | 29826.0 | nM | 4.53 |
| CHEMBL3926548 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3954187 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3962920 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3926810 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3973883 | — | IC50 | > | 100000.0 | nM | - |