Assay Detail
Functional
CHEMBL4001873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma brucei bloodstream forms after 72 hrs by CellTiter-Blue fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Evaluation of substituted ebselen derivatives as potential trypanocidal agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.53 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL45152 | — | — | 1 | 7.52 |
| CHEMBL51085 | EBSELEN | 3.0 | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL45152 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL51085 | EBSELEN | EC50 | = | 2900.0 | nM | 5.54 |