Assay Detail
ADMET
CHEMBL4010627
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Inhibition of recombinant human CYP2C9 expressed in baculosomes using Vivid OOMR substrate red measured every 30 sec for 30 mins by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.96 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1095671 | — | — | 1 | 5.17 |
| CHEMBL402978 | GINGEROL | -1.0 | 1 | 4.92 |
| CHEMBL549472 | — | — | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1095671 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL402978 | GINGEROL | IC50 | = | 12100.0 | nM | 4.92 |
| CHEMBL549472 | — | IC50 | = | 16300.0 | nM | 4.79 |