Assay Detail
Binding
CHEMBL4014607
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.47 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | 4.0 | 1 | 9.52 |
| CHEMBL48435 | — | — | 1 | 9.10 |
| CHEMBL298727 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL603 | ZAFIRLUKAST | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL48435 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL298727 | — | Ki | = | 157.0 | nM | 6.80 |