Assay Detail
Binding
CHEMBL4014608
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ICI from cysteinyl leukotriene receptor 1 in Hartley guinea pig lung membrane after 30 mins by liquid scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Lung |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.17 | 10.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL21333 | PRANLUKAST | 4.0 | 1 | 10.36 |
| CHEMBL4102154 | — | — | 1 | 7.52 |
| CHEMBL174483 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL21333 | PRANLUKAST | IC50 | = | 0.044 | nM | 10.36 |
| CHEMBL4102154 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL174483 | — | IC50 | = | 240.0 | nM | 6.62 |