Assay Detail
Functional
CHEMBL4025748
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human DU145 cells after 24 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 4.12 | 4.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4099982 | — | — | 1 | 4.12 |
| CHEMBL4077464 | — | — | 1 | - |
| CHEMBL4059948 | — | — | 1 | - |
| CHEMBL4091788 | — | — | 1 | - |
| CHEMBL4064849 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4099982 | — | EC50 | = | 76500.0 | nM | 4.12 |
| CHEMBL4077464 | — | EC50 | > | 80000.0 | nM | - |
| CHEMBL4059948 | — | EC50 | > | 80000.0 | nM | - |
| CHEMBL4091788 | — | EC50 | > | 80000.0 | nM | - |
| CHEMBL4064849 | — | EC50 | > | 80000.0 | nM | - |