Assay Detail
Binding
CHEMBL4025933
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Equus caballus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.53 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4084610 | — | — | 1 | 8.70 |
| CHEMBL51197 | — | — | 1 | 7.46 |
| CHEMBL540199 | — | — | 1 | 6.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4084610 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL51197 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL540199 | — | IC50 | = | 380.0 | nM | 6.42 |